{"id":1078,"date":"2020-12-03T09:52:06","date_gmt":"2020-12-03T09:52:06","guid":{"rendered":"http:\/\/leokings.com\/leokings-wp\/?p=1078"},"modified":"2020-12-03T09:52:06","modified_gmt":"2020-12-03T09:52:06","slug":"november-2020","status":"publish","type":"post","link":"http:\/\/leokings.com\/leokings-wp\/november-2020\/","title":{"rendered":"November 2020"},"content":{"rendered":"<p>Another sad month for us as our old boy Yogi passed away peacefully . Always a very healthy boy , his age finally caught up with him .He was very nearly 10 years old ,<\/p>\n<p>RIP our big soft teddy bear , you are much missed . Our home really feels quiet now with only our Prada and Baloo left , plus Daisy our Cockapoo .<\/p>\n<p>There was an announcement of another test for Leonbergers , this one called LPPN3 . This is from the researchers below ,<\/p>\n<div>\n<div class=\"\" dir=\"auto\">\n<div id=\"jsc_c_1f9\" class=\"dati1w0a ihqw7lf3 hv4rvrfc ecm0bbzt\">\n<div class=\"bi6gxh9e\"><span class=\"d2edcug0 hpfvmrgz qv66sw1b c1et5uql rrkovp55 jq4qci2q a3bd9o3v knj5qynh oo9gr5id\">The LPPN3 mutation is inherited in an autosomal recessive manner meaning that two copies of the mutation are required to show signs of disease (LPPN3-D\/D). LPPN3 affected Leonberger dogs typically develop\u00a0<b>severe laryngeal paralysis<\/b>\u00a0at a young age, with most affected dogs requiring laryngeal tieback surgery. Additional clinical signs, which were noted variably among the dogs, included difficulty swallowing, changes in barking frequency and quality, high-stepping and uncoordinated gait, stumbling and tripping, exercise intolerance, and muscle atrophy. Like many neurological diseases, there is no effective treatment for LPN. Since in most cases the dog is not in pain but is strongly restricted in its quality of life, especially due to the frequent loss of normal function of the larynx, owners are encouraged to ask a veterinarian for advice.<\/span><\/div>\n<ul class=\"bi6gxh9e aov4n071 fjf4s8hc mf5omzu7\">\n<li>\n<div class=\"bi6gxh9e\"><span class=\"d2edcug0 hpfvmrgz qv66sw1b c1et5uql rrkovp55 jq4qci2q a3bd9o3v knj5qynh oo9gr5id\">This mutation explains ~3% of all diagnosed cases of laryngeal paralysis-polyneuropathy in Leonbergers (average onset 3.5 years); population testing of &gt;2,700 Leonbergers indicates that the carrier rate is ~11%.<\/span><\/div>\n<\/li>\n<li>\n<div class=\"bi6gxh9e\"><span class=\"d2edcug0 hpfvmrgz qv66sw1b c1et5uql rrkovp55 jq4qci2q a3bd9o3v knj5qynh oo9gr5id\">This mutation explains ~40% of young onset laryngeal paralysis-polyneuropathy within the Saint Bernard (average onset 2 years); population testing of &gt;300 Saint Berndards indicates that the carrier rate is ~20%.<\/span><\/div>\n<\/li>\n<li>\n<div class=\"bi6gxh9e\"><span class=\"d2edcug0 hpfvmrgz qv66sw1b c1et5uql rrkovp55 jq4qci2q a3bd9o3v knj5qynh oo9gr5id\">This mutation has also been found to be a rare cause of laryngeal paralysis-polyneuropathy in Labrador retrievers (especially younger Labradors, average onset 7.5 years); population testing of &gt;1,500 Labrador retrievers indicates that the carrier rate is ~10%.<\/span><\/div>\n<\/li>\n<li>\n<div class=\"bi6gxh9e\"><span class=\"d2edcug0 hpfvmrgz qv66sw1b c1et5uql rrkovp55 jq4qci2q a3bd9o3v knj5qynh oo9gr5id\">We have also identified LPPN3-D\/D affected mixed breed dogs, and the mutation is present in several breeds.<\/span><\/div>\n<\/li>\n<\/ul>\n<p>All breeding dogs need to be tested to avoid putting two carriers together in the future .\u00a0 Test results can be viewed on the Worldwide Leonberger Database for this mutation and also LPN1 and LPN2 and Lemp . If you are looking for a puppy , please do ensure that you actually view all health test results and save yourself the heartache of having an affected puppy .<\/p>\n<p>We were very happy to learn that two of Zorros pups reached their 11th birthday in Australia . Congratulations to Ramius ( Gr Ch Adlihtam Hunt for Red October ) and Keira<\/p>\n<p>Ramius 11 years old<\/p>\n<p><img loading=\"lazy\" class=\"size-full wp-image-1079 aligncenter\" src=\"http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/Ramius-11-years-old.jpg\" alt=\"Ramius 11 years old\" width=\"911\" height=\"728\" srcset=\"http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/Ramius-11-years-old.jpg 911w, http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/Ramius-11-years-old-300x240.jpg 300w, http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/Ramius-11-years-old-768x614.jpg 768w\" sizes=\"(max-width: 911px) 100vw, 911px\" \/><\/p>\n<\/div>\n<\/div>\n<\/div>\n<div>\n<div class=\"stjgntxs ni8dbmo4 l82x9zwi uo3d90p7 h905i5nu monazrh9\" data-visualcompletion=\"ignore-dynamic\">\n<div>\n<div class=\"l9j0dhe7\">\n<div class=\"bp9cbjyn m9osqain j83agx80 jq4qci2q bkfpd7mw a3bd9o3v kvgmc6g5 wkznzc2l oygrvhab dhix69tm jktsbyx5 rz4wbd8a osnr6wyh a8nywdso s1tcr66n\">\n<div class=\"kb5gq1qc pfnyh3mw c0wkt4kp\"><\/div>\n<div class=\"bp9cbjyn j83agx80 pfnyh3mw p1ueia1e\">\n<div class=\"gtad4xkn\">\n<div class=\"oajrlxb2 g5ia77u1 qu0x051f esr5mh6w e9989ue4 r7d6kgcz rq0escxv nhd2j8a9 nc684nl6 p7hjln8o kvgmc6g5 cxmmr5t8 oygrvhab hcukyx3x jb3vyjys rz4wbd8a qt6c0cv9 a8nywdso i1ao9s8h esuyzwwr f1sip0of lzcic4wl l9j0dhe7 abiwlrkh gpro0wi8 dwo3fsh8 ow4ym5g4 auili1gw du4w35lb gmql0nx0\" tabindex=\"0\"><span class=\"d2edcug0 hpfvmrgz qv66sw1b c1et5uql rrkovp55 a8c37x1j keod5gw0 nxhoafnm aigsh9s9 d3f4x2em fe6kdd0r mau55g9w c8b282yb iv3no6db jq4qci2q a3bd9o3v knj5qynh m9osqain\" dir=\"auto\">\u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 \u00a0 We received this lovely photo of Bertie now 2 years old from our last litter . Bertie is a huge boy weighing in at 83 kg\u00a0<\/span><\/div>\n<div class=\"oajrlxb2 g5ia77u1 qu0x051f esr5mh6w e9989ue4 r7d6kgcz rq0escxv nhd2j8a9 nc684nl6 p7hjln8o kvgmc6g5 cxmmr5t8 oygrvhab hcukyx3x jb3vyjys rz4wbd8a qt6c0cv9 a8nywdso i1ao9s8h esuyzwwr f1sip0of lzcic4wl l9j0dhe7 abiwlrkh gpro0wi8 dwo3fsh8 ow4ym5g4 auili1gw du4w35lb gmql0nx0\" tabindex=\"0\"><img loading=\"lazy\" class=\"alignnone size-full wp-image-1081\" src=\"http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/bertie-2-years.jpg\" alt=\"bertie 2 years\" width=\"2048\" height=\"1536\" srcset=\"http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/bertie-2-years.jpg 2048w, http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/bertie-2-years-300x225.jpg 300w, http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/bertie-2-years-768x576.jpg 768w, http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/bertie-2-years-1024x768.jpg 1024w, http:\/\/leokings.com\/leokings-wp\/wp-content\/uploads\/2020\/12\/bertie-2-years-320x240.jpg 320w\" sizes=\"(max-width: 2048px) 100vw, 2048px\" \/><\/div>\n<\/div>\n<div class=\"oajrlxb2 g5ia77u1 qu0x051f esr5mh6w e9989ue4 r7d6kgcz rq0escxv nhd2j8a9 nc684nl6 p7hjln8o kvgmc6g5 cxmmr5t8 oygrvhab hcukyx3x jb3vyjys rz4wbd8a qt6c0cv9 a8nywdso i1ao9s8h esuyzwwr f1sip0of lzcic4wl l9j0dhe7 abiwlrkh gpro0wi8 dwo3fsh8 ow4ym5g4 auili1gw du4w35lb gmql0nx0\" tabindex=\"0\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"a8nywdso e5nlhep0 rz4wbd8a ecm0bbzt dhix69tm oygrvhab wkznzc2l kvgmc6g5 k7cz35w2 jq4qci2q j83agx80 olo4ujb6 jmbispl3\">\n<div class=\"oajrlxb2 bp9cbjyn g5ia77u1 mtkw9kbi tlpljxtp qensuy8j ppp5ayq2 goun2846 ccm00jje s44p3ltw mk2mc5f4 rt8b4zig n8ej3o3l agehan2d sk4xxmp2 rq0escxv nhd2j8a9 j83agx80 rj1gh0hx btwxx1t3 pfnyh3mw p7hjln8o kvgmc6g5 cxmmr5t8 oygrvhab hcukyx3x tgvbjcpo hpfvmrgz jb3vyjys rz4wbd8a qt6c0cv9 a8nywdso l9j0dhe7 i1ao9s8h esuyzwwr f1sip0of du4w35lb lzcic4wl abiwlrkh p8dawk7l buofh1pr k7cz35w2 taijpn5t ms05siws flx89l3n ogy3fsii\" tabindex=\"0\">\n<div class=\"n00je7tq arfg74bv qs9ysxi8 k77z8yql i09qtzwb n7fi1qx3 b5wmifdl hzruof5a pmk7jnqg j9ispegn kr520xx4 c5ndavph art1omkt ot9fgl3s\" data-visualcompletion=\"ignore\"><\/div>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"cwj9ozl2 tvmbv18p\"><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Another sad month for us as our old boy Yogi passed away peacefully . Always a very healthy boy , his age finally caught up with him .He was very nearly 10 years old , RIP our big soft teddy bear , you are much missed . Our home really feels quiet now with only [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[20],"tags":[],"_links":{"self":[{"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/posts\/1078"}],"collection":[{"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/comments?post=1078"}],"version-history":[{"count":1,"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/posts\/1078\/revisions"}],"predecessor-version":[{"id":1082,"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/posts\/1078\/revisions\/1082"}],"wp:attachment":[{"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/media?parent=1078"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/categories?post=1078"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/leokings.com\/leokings-wp\/wp-json\/wp\/v2\/tags?post=1078"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}